Depression in adolescence can lead to dementia in old age, research

Depression in adolescence can lead to dementia in old age, says
research So the decline of mental capacity (cognition) in middle age or old age can be prevented.
However, adversity can also lead to dementia and dementia in old age. The study, by scientists at the University of California, San Francisco, was published in the journal Alzheimer’s Disease on September 28. Scientists have adopted an innovative approach. It looks at the prognosis in 15,000 people between the ages of 20 and 89 and the possible consequences. It was found that 6,000 elderly people were found to be suffering from depression in their youth and the risk of brain and acquired degeneration was found to be 73% higher than others.
Experts in the study also included diet, lifestyle, age, sex, nationality, education, body mass index, diabetes and smoking. Scientist Villa Brainows explains why stress causes the release of hormones called glucocorticoids, which directly damage the hippocampus, an important part of the brain. In the hippocampus, our thinking is formed, thoughts are organized and memories begin to be organized. It should be noted that in this entire study, all participants were contacted twice a year for eleven years and questionnaires were filled out for them. It can be used to diagnose the symptoms of depression, ie mild, moderate and severe. At the beginning of the research, 13 in the youth Some 26% of middle-aged people and 34% of the elderly had some degree of depression. Of these, 1277 people were found to be suffering from some degree of mental retardation. Therefore, it is important that if depression is reduced today, it can prevent dementia in old age.


Eat grapes to lower cholesterol

If you want to lower your cholesterol, eat grapes! More recent research has found that grapefruit, grape juice, or ‘phenol’ compounds derived from grapes, in addition to antioxidants, are effective against germs and viruses. Performed by Dr. Xiaoping and his colleagues in Los Angeles, California. During the first four weeks, all volunteers were placed on a low-polyphenol diet, followed by a dry diet for the next four weeks. Only 46 grams of grapefruit powder was added daily. This amount of grapefruit juice was equivalent to 252 grams of fresh grapes.
Los Angeles: American medical experts have discovered that eating just one pound (252 grams) of grapes or raisins a day lowers harmful cholesterol in the body. After the discovery which lasted for 8 weeks. Volunteers ranged in age from 18 to 55. The medical benefits of grapes have been known to us for centuries, while modern scientific research has shown that they contain a variety of beneficial plant compounds, ie phytochemicals, including catechins. , Pro Anthocyanidins, Anthocyanins, Leuko Anthocyanidins, Quercetin, Campferol, Stalbins, Allergic Acids and Hydrosanamites. In addition, grapes are rich in dietary fiber.

Before and after the study began, all volunteers underwent cholesterol and bile acids (bile acids) as well as their microbiome in their stomachs. After consuming 46 grams of grapefruit powder daily, the total cholesterol in these volunteers was reduced by 6.1% while the unhealthy cholesterol (LDL) was reduced by 5.9%. There was an increase in the number of germs which was undoubtedly good news. Among them there was an increase in a type of germs called “acarmenasia” which helps in breaking down and digesting glucose and fats while the lining of the intestines. The amount of bile acids that affect the digestion of cholesterol is also 40 at the end of the study.9% less is seen which is a sign of better health. “We have discovered the beneficial effects of grapes on stomach germs which is a great thing, because keeping the stomach healthy is very important for good health,” said Dr. Lee said.
Note: Details of this research are published in the latest issue of the online research journal “Nutrients”.

Health News Science

A molecule in the body could be the cause of multiple sclerosis

Researchers trying to understand the cause of the destructive activity of the immune system in people with multiple sclerosis may have discovered the molecule triggering the attack on the nervous system.

Autoimmune diseases are today a real source of concern in Western countries. They are now considered the third leading cause of death, after cancer and cardiovascular diseases, although they have by far not the reputation of the latter. Indeed, many people have never heard of this term.

Autoimmune diseases are caused by a reversal of the defences against the very organism that they are supposed to protect.

During an infection, the immune cells recognize antigens, molecules – often proteins – which come specifically from the infectious agent. This makes it possible to activate, in the place of invasion, the various mechanisms which will “stimulate” the body’s defences in order to eradicate the intruding microorganisms.

In autoimmune diseases, the immune system would confuse molecules produced by its own organism with antigens, leading the latter to destroy the parts of the body or organs where they are located. These molecules, mistakenly considered as threats, are called “autoantigens”.

In the case of multiple sclerosis (MS), the part attacked in the body is myelin, a kind of envelope protecting the nerves, and also allowing them to propagate nerve messages more quickly. When this sheath is damaged, serious neurological consequences ensue: loss of sight, sensitivity, muscle tone … and these often lead to paralysis.

Specialists have obviously suspected that autoantigens must be located on myelin. After many years of research, no culprit has been identified so far, but immunologists at the University Hospital of Zurich published this week the discovery of a suspicious molecule.

The group worked on T lymphocytes, a type of immune cell that reacts to contact with fragments of antigens of bacterial or viral origin (epitopes), but which is also involved in multiple sclerosis. They obtained these cells from MS patients and incorporated them into mixtures of more than 200 protein fragments, each with more than 200 billion varieties.

They found that two of the fragments strongly reacted the T lymphocytes and that they were constituents of the same protein, guanosine diphosphate-L-fucose synthase (GD-L-FS), an enzyme involved in the metabolism of certain sugars, in memory, but also in the determination of the blood group.

Of the 31 volunteers with the disease (or showing early symptoms), 12 of them saw their lymphocytes react to the enzyme.

The researchers then tested whether the bacterial version of the enzyme also caused a reaction on the immune cells of 8 patients. The T lymphocytes of four of them reacted to the presence of this enzyme, thus giving more credibility to a research carried out last year, which suspected that certain bacteria of the intestinal flora could trigger the disease.

However, immunologist Ashutosh Mangalam of the University of Iowa warns that the latter result should be taken with tweezers. ”  Some of the bacteria that produce the enzyme are less abundant in MS patients than in healthy people,  ” he says.

Reinhard Hohlfeld, of Ludwig Maximilians University in Munich, considers the discovery of the likely involvement of GD-L-FS as the first step in an interesting new direction. Although this enzyme is widespread in the brain, ”  it never was a candidate,  ” he says.

Zurich researchers predict that if future research clearly confirms GD-L-FS as an autoantigen, one of the possible clinical applications would be the same as for allergies, i.e. injections of the molecule so that the immune system reacts less and less. They even plan to test this strategy on patients from next year.

Source: Science Translational Medicine

Overlooked Mental Disorders

The brilliant Dr Syeda Maria Bukhari, a dedicated psychologist, unravelled a subject rarely ever discussed. She shed significant light upon mental disorders, their symptoms, aetiology and treatment. It was shocking to learn that there has been a rise in mental illnesses in Pakistan. Most patients never get diagnosed due to a lack of awareness of the subject. Patients get no treatment and almost always suffer till they die. What a horrible revelation! People are suffering all around us and we are quite oblivious to their plight. The loved ones around a patient judge him/her to be crazy and self-centred. Most assume the sufferer to be afflicted by the supernatural. They are either left alone or taken to peers to find a spiritual cure. This is a tiny effort to create some awareness for the oblivious ones and for those who suffer in silence.

There are over 200 classified mental disorders. This article talks about a common few like:
• Depression
• Anxiety disorders
• Bipolar disorder
• Schizophrenia

Depression is the most undermined mental illness. It is just characterized as persistently low mood and a loss of interest. But it is so much more than that. It is an actual illness that affects many; men and women. The average length of a depressive episode is 6-8 months. Sadness, mood swings, hopelessness, guilt, angry outbursts and loss of interest in pleasurable activities are a few symptoms of depression.
It is further subdivided into:
• Major depression
• Persistent Depressive disorder
• Bipolar disorder
• Seasonal Affective Disorder (SAD)
• Psychotic Depression
• Postpartum Depression
• Premenstrual Dysphoric Disorder (PMDD)
• Situational Depression
• Atypical Depression

Depression physically affects in numerous ways. The patient feels unexplained aches, weight loss/gain, change in appetite, tiredness or lack of energy and sexual problems. There are sudden behavioural changes. He/she finds it difficult to honour commitments withdraws from people, self-harms and indulges in substance abuse. Decision making, concentrating, remembering are all difficult for a person suffering from depression. Delusions and hallucinations also occur in severe forms of depression.
Depression has numerous causes. It can be caused by genes, a chemical imbalance in the brain and hormonal changes. It can even be caused by seasons. Traumatic experiences like assault, abuse, accidents, life-threatening situations and childhood traumas also trigger depression in many people.
Depression is treatable. Intervention by loved ones is important. If you feel a certain loved one around you has these symptoms or you have any of these symptoms, please visit a psychologist for diagnoses. Along with that exercising, eating healthy and changes in lifestyle also help in eradicating this disorder.

The next disorder on this list is:

Anxiety Disorder and Panic Attacks:

Some of the most commonly diagnosed anxiety disorders are:
Generalized anxiety disorder (GAD)
This disorder is basically feeling anxious and fearful for no reason.
Panic disorder
People suffering from panic disorders have unpredictable panic attacks triggered by unknown reasons.
Obsessive-compulsive disorder (OCD)
Obsessions and repetitive activities like washing your hands over and over again.
The person suffering from phobias is intensely fearful of harmless objects.
Post-traumatic stress disorder (PTSD)
PTSD causes flashbacks and nightmares of traumatic experiences and makes the patient relive those agonizing moments over and over again.

A few symptoms of anxiety disorders are; nervousness, panic, sweating, trembling, increased heart rate, rapid breathing, trouble sleeping and gastrointestinal problems. Causes of anxiety disorders aren’t fully understood. They are most probably triggered by traumas or genes. Cognitive-behavioural therapy is very effective in treating these disorders.

Bipolar Disorder:
It is also known as manic-depressive disorder. Most people suffering from this disorder cycle between depression and mania. A few symptoms are; rapid, loud and uninterruptable speech, hyperactivity, decreased sleep, excessive spending, hypersexuality and substance abuse.
It is caused by genes, environment and dysfunction of neurotransmitters in the brain. It is treated by medication prescribed by a practising doctor.

Schizophrenia is caused by factors like genes and environment. Schizophrenic people have different brains as compared to people who do not suffer from schizophrenia. There are fewer connections between brain cells and the parts of the brain that deal with memory are smaller. Schizophrenic patients have various emotional, cognitive and behavioural problems.
A person suffering from schizophrenia may have impaired communication, abnormal motor behaviour and lack of ability to function. This includes a lack of emotions and neglecting personal hygiene. They have delusions based on false beliefs, they assume to be harassed or famous. They could assume certain gestures are made against them whereas, in reality, those gestures have nothing to do with them. They have hallucinations, they hear and see things which are not real but for them they are real. Voices coerce them to inflict pain on themselves or others around them.
People suffering from this disorder have no concept of the reality around them. They live in a world of their own which adversely affects them and their loved ones. If the patient is left untreated this disease can worsen and can end in suicide or aggressive behaviour. If you see symptoms of schizophrenia in someone around you, talk to them and try to convince them to seek help from a mental health professional. It may be hard to convince the sufferer but it is absolutely essential that they receive medical help.

COVID-19 Health News

Corona: ‘Immunity may end soon’

New research on the coronavirus and the human body’s immune system suggests that people who recover from the infection may lose or lose their immunity in a matter of months.
Experts say the study could have a profound effect on governments’ ways of dealing with the Corona epidemic, according to AFP.
The first study of its kind was conducted by a team of researchers at King’s College London. They looked at antibody levels in 90 patients and saw how they changed over time.
About 60% of the patients who took part in the study had higher levels of resistance to the virus. However, after three months, only 16.7% of the patients had more antibodies against code 19, while after 90 days, no antibodies were found in the blood of some patients.
When a virus enters a person’s body from outside, the body’s cells move to kill it. During this time, proteins called antibodies are produced in the body that helps fight this particular danger.
If a person has plenty of antibodies in their body, they can get rid of new infections, and develop immunity. However, according to research released on Monday, the immune system does not stay in the body all the time, but only for a few days, as in other viruses such as influenza.
Experts say the study could change the government’s plans to fight the corona epidemic. Lawrence Young, a professor at Warwick University who was not part of the study, said the research could help create an effective vaccine because it could provide important information about immunity.

COVID-19 Entertainment Health News

After Amitabh and Abhishek, Aishwarya Rai is also Corona

After the corona test of Bollywood actor Amitabh Bachchan and his son Abhishek Bachchan came positive, the corona report of Abhishek’s wife Aishwarya Rai Bachchan and daughter Aradhya Bachchan also came positive.
Maharashtra Health Minister Rajesh Tope tweeted about it.

Rajesh Tope has said that Amitabh Bachchan’s wife Jaya Bachchan’s code 19 report has been negative.

On social media, on the other hand, well-known actress and BJP MP Hema Malani were rumored to be unwell, in response to which Dream Girl said in a video message on Twitter that the rumor was false and that she was healthy.

Meanwhile, Bollywood actor Anupam Kher has tweeted that her mother has received a positive report from Corona. The report of his brother, sister-in-law, and niece in this house has also come positive but their report has come negative.

Earlier, Bollywood actor Amitabh Bachchan and his son Abhishek Bachchan were shifted to hospital after testing positive for corona.

In a message posted on the micro-blogging website Twitter, Amitabh Bachchan and Abhishek Bachchan confirmed that the relevant agencies were being informed after the hospitalization.

In his message, he also clarified that the family and their staff have also undergone diagnostic tests for the coronavirus and are now awaiting test reports.

In his tweet, Amitabh Bachchan said that those who have been close to him during the last 10 days are requested to get their tests done.

Shortly after Amitabh Bachchan’s message, his son Abhishek Bachchan announced that his Corona test was also positive. “We both have minor symptoms and are hospitalized,” he wrote in his message.

The 77-year-old Bollywood legend, who was admitted to Mumbai’s Nana Vati Hospital, was reportedly tested positive for the Korna virus and people from various walks of life wished him a speedy recovery.

Former Pakistani cricketer Shoaib Akhtar in his message wished him a speedy recovery and also spoke to his fans on both sides of the border.

Indian actress Sonam’s Ahuja also wished her a speedy recovery in her Twitter message.

Union Health Minister Dr. Harsh Vardhan wrote in his response to Amitabh Bachchan’s tweet, “I wish you a speedy recovery together with the entire nation.” You are the superstar for millions in this country. We will take good care of you.

When cases of the coronavirus began to surface in March, Amitabh Bachchan tweeted that he had “quarantined the house”. In his message, he appealed to be safe and cautious and isolated if positive.

After the news of Amitabh Bachchan’s corona test coming out positive, his name and the name of Nanavati Hospital became part of the trends list. Amitabh Bachchan lives in Mumbai, one of the most affected Indian cities by the coronavirus. According to Indian media reports, more than 91,000 corona cases have been reported in Mumbai while the death toll has crossed 5,200.